Scientific illustration for Minor Cannabinoid Use Among Medical Cannabis Patients.

Minor Cannabinoid Use Among Medical Cannabis Patients.

Journal of psychoactive drugs β€’ β€’ Highly Relevant
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AI Summary

As cannabis legalization spreads across the United States, new types of cannabinoids beyond the well-known THC and CBD are becoming increasingly available to patients. This research surveyed over 1,700 medical cannabis patients to understand who is using these emerging cannabinoidsβ€”such as delta-8 THC, CBG, CBN, and THC-Oβ€”and why. The study found that patients are actively using a diverse range of these newer products, with many using them daily. The most popular cannabinoids were CBD, regular delta-9 THC, delta-8 THC, and THCA, consumed primarily through smoking flower, vape pens, and edibles.

Beyond just documenting usage patterns, the research revealed important motivations behind these choices. Most patients reported using cannabis to manage medical conditions and improve their overall well-being, and notably, the majority said they had reduced or stopped taking conventional pharmaceuticals because of their medical cannabis use. This finding suggests that patients may be self-treating conditions and potentially replacing traditional medications with cannabis products, a practice with significant health implications.

The study's main takeaway is a call to action: as these emerging cannabinoids become more widely available and used, there's an urgent need for better public education and health information. Patients are experimenting with novel cannabinoids without clear guidance about their effects, safety, or how they compare to established options. This research highlights a gap between product availability and scientific understandingβ€”we need more research on these emerging cannabinoids and better communication to help patients make informed decisions about their medical use.

πŸ’‘ Key Findings

1
Medical cannabis patients are frequently using emerging cannabinoids including delta-8 THC, CBG, CBN, and THC-O, with many reporting daily use patterns similar to established cannabinoids like CBD and delta-9 THC.
High
95%
2
The majority of surveyed patients reported discontinuing or reducing use of pharmaceutical medications and other drugs after starting medical cannabis, indicating they may be using cannabis as a substitute for conventional treatments.
High
92%
3
Patients prefer smoking flower, vape pens/cartridges, and edibles as delivery methods for nearly all cannabinoid types, suggesting consistent consumption preferences across different cannabinoids.
High
93%
4
There is currently a significant knowledge gap regarding emerging cannabinoidsβ€”patients are actively using novel products without sufficient public health education or scientific guidance about their effects and safety profiles.
High
90%

πŸ“„ Original Abstract

The legalization of cannabis in the United States (US) has increased the availability of a variety of novel cannabinoids such as cannabigerol (CBG) and cannabinol (CBN), delta-8 tetrahydrocannabinol (delta-8 THC) and THC-O acetate ester (THC-O), yet little is understood about the use of these emerging cannabinoids by medical cannabis patients. A large sample (N = 1721) of US medical cannabis patients was surveyed to characterize their patterns of use (frequency, methods of administration) and motivations for use, across a wide variety of emerging cannabinoids. Results revealed that participants most frequently endorsed past year use of cannabidiol (CBD), delta-9-THC, delta-8-THC, and THCA, with daily use commonly reported. Participants most frequently endorsed smoking flower, using a vape pen/cartridge, and use of edibles to administer nearly all cannabinoids. They most frequently reported using cannabis to treat medical conditions, for well-being, and as a substitute for medications, and the majority reported that they had stopped using one or more pharmaceuticals or other drugs because of their medical cannabis use. Our survey demonstrates the substantial use of emerging cannabinoid products among a large sample of medical cannabis patients and indicates that public health outreach is needed to help educate people about these emerging cannabinoids.

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